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eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation

Published Web Location

https://doi.org/10.1038/nature18954
Abstract

The initiation protein eIF3d serves as an alternative cap-recognition factor for a subclass of mRNAs, such as c-Jun; the high-resolution structure of the eIF3d cap-binding domain can be modelled onto the cap structure, defining interactions that are needed for translation of these mRNAs.

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