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Functional role of DNA mismatch repair gene PMS2 in prostate cancer cells
- Dahiya, Rajvir;
- Fukuhara, S;
- Chang, I;
- Mitsui, Y;
- Chiyomaru, T;
- Yamamura, S;
- Majid, S;
- Saini, S;
- Deng, G;
- Gill, A;
- Wong, DK
Published Web Location
http://europepmc.org/articles/PMC4599273?pdf=renderNo data is associated with this publication.
Abstract
DNA mismatch repair (MMR) enzymes act as proofreading complexes that maintains genomic integrity and MMR-deficient cells show an increased mutation rate. MMR has also been shown to influence cell signaling and the regulation of tumor development. MMR consi
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