Skip to main content
Weak base pairing in both seed and 3' regions reduces RNAi off-targets and enhances si/shRNA designs
Published Web Location
http://europepmc.org/articles/PMC4231738?pdf=renderNo data is associated with this publication.
Abstract
© The Author(s) 2014.The use of RNA interference is becoming routine in scientific discovery and treatment of human disease. However, its applications are hampered by unwanted effects, particularly off-targeting through miRNA-like pathways. Recent studies
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.