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Open Access Publications from the University of California

Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.

  • Author(s): Leung, Wilson
  • Shaffer, Christopher D
  • Reed, Laura K
  • Smith, Sheryl T
  • Barshop, William
  • Dirkes, William
  • Dothager, Matthew
  • Lee, Paul
  • Wong, Jeannette
  • Xiong, David
  • Yuan, Han
  • Bedard, James EJ
  • Machone, Joshua F
  • Patterson, Seantay D
  • Price, Amber L
  • Turner, Bryce A
  • Robic, Srebrenka
  • Luippold, Erin K
  • McCartha, Shannon R
  • Walji, Tezin A
  • Walker, Chelsea A
  • Saville, Kenneth
  • Abrams, Marita K
  • Armstrong, Andrew R
  • Armstrong, William
  • Bailey, Robert J
  • Barberi, Chelsea R
  • Beck, Lauren R
  • Blaker, Amanda L
  • Blunden, Christopher E
  • Brand, Jordan P
  • Brock, Ethan J
  • Brooks, Dana W
  • Brown, Marie
  • Butzler, Sarah C
  • Clark, Eric M
  • Clark, Nicole B
  • Collins, Ashley A
  • Cotteleer, Rebecca J
  • Cullimore, Peterson R
  • Dawson, Seth G
  • Docking, Carter T
  • Dorsett, Sasha L
  • Dougherty, Grace A
  • Downey, Kaitlyn A
  • Drake, Andrew P
  • Earl, Erica K
  • Floyd, Trevor G
  • Forsyth, Joshua D
  • Foust, Jonathan D
  • Franchi, Spencer L
  • Geary, James F
  • Hanson, Cynthia K
  • Harding, Taylor S
  • Harris, Cameron B
  • Heckman, Jonathan M
  • Holderness, Heather L
  • Howey, Nicole A
  • Jacobs, Dontae A
  • Jewell, Elizabeth S
  • Kaisler, Maria
  • Karaska, Elizabeth A
  • Kehoe, James L
  • Koaches, Hannah C
  • Koehler, Jessica
  • Koenig, Dana
  • Kujawski, Alexander J
  • Kus, Jordan E
  • Lammers, Jennifer A
  • Leads, Rachel R
  • Leatherman, Emily C
  • Lippert, Rachel N
  • Messenger, Gregory S
  • Morrow, Adam T
  • Newcomb, Victoria
  • Plasman, Haley J
  • Potocny, Stephanie J
  • Powers, Michelle K
  • Reem, Rachel M
  • Rennhack, Jonathan P
  • Reynolds, Katherine R
  • Reynolds, Lyndsey A
  • Rhee, Dong K
  • Rivard, Allyson B
  • Ronk, Adam J
  • Rooney, Meghan B
  • Rubin, Lainey S
  • Salbert, Luke R
  • Saluja, Rasleen K
  • Schauder, Taylor
  • Schneiter, Allison R
  • Schulz, Robert W
  • Smith, Karl E
  • Spencer, Sarah
  • Swanson, Bryant R
  • Tache, Melissa A
  • Tewilliager, Ashley A
  • Tilot, Amanda K
  • VanEck, Eve
  • Villerot, Matthew M
  • Vylonis, Megan B
  • Watson, David T
  • Wurzler, Juliana A
  • Wysocki, Lauren M
  • Yalamanchili, Monica
  • Zaborowicz, Matthew A
  • Emerson, Julia A
  • Ortiz, Carlos
  • Deuschle, Frederic J
  • DiLorenzo, Lauren A
  • Goeller, Katie L
  • Macchi, Christopher R
  • Muller, Sarah E
  • Pasierb, Brittany D
  • Sable, Joseph E
  • Tucci, Jessica M
  • Tynon, Marykathryn
  • Dunbar, David A
  • Beken, Levent H
  • Conturso, Alaina C
  • Danner, Benjamin L
  • DeMichele, Gabriella A
  • Gonzales, Justin A
  • Hammond, Maureen S
  • Kelley, Colleen V
  • Kelly, Elisabeth A
  • Kulich, Danielle
  • Mageeney, Catherine M
  • McCabe, Nikie L
  • Newman, Alyssa M
  • Spaeder, Lindsay A
  • Tumminello, Richard A
  • Revie, Dennis
  • Benson, Jonathon M
  • Cristostomo, Michael C
  • DaSilva, Paolo A
  • Harker, Katherine S
  • Jarrell, Jenifer N
  • Jimenez, Luis A
  • Katz, Brandon M
  • Kennedy, William R
  • Kolibas, Kimberly S
  • LeBlanc, Mark T
  • Nguyen, Trung T
  • Nicolas, Daniel S
  • Patao, Melissa D
  • Patao, Shane M
  • Rupley, Bryan J
  • Sessions, Bridget J
  • Weaver, Jennifer A
  • Goodman, Anya L
  • Alvendia, Erica L
  • Baldassari, Shana M
  • Brown, Ashley S
  • Chase, Ian O
  • Chen, Maida
  • Chiang, Scott
  • Cromwell, Avery B
  • Custer, Ashley F
  • DiTommaso, Tia M
  • El-Adaimi, Jad
  • Goscinski, Nora C
  • Grove, Ryan A
  • Gutierrez, Nestor
  • Harnoto, Raechel S
  • Hedeen, Heather
  • Hong, Emily L
  • Hopkins, Barbara L
  • Huerta, Vilma F
  • Khoshabian, Colin
  • LaForge, Kristin M
  • Lee, Cassidy T
  • Lewis, Benjamin M
  • Lydon, Anniken M
  • Maniaci, Brian J
  • Mitchell, Ryan D
  • Morlock, Elaine V
  • Morris, William M
  • Naik, Priyanka
  • Olson, Nicole C
  • Osterloh, Jeannette M
  • Perez, Marcos A
  • Presley, Jonathan D
  • Randazzo, Matt J
  • Regan, Melanie K
  • Rossi, Franca G
  • Smith, Melanie A
  • Soliterman, Eugenia A
  • Sparks, Ciani J
  • Tran, Danny L
  • Wan, Tiffany
  • Welker, Anne A
  • Wong, Jeremy N
  • Sreenivasan, Aparna
  • Youngblom, Jim
  • Adams, Andrew
  • Alldredge, Justin
  • Bryant, Ashley
  • Carranza, David
  • Cifelli, Alyssa
  • Coulson, Kevin
  • Debow, Calise
  • Delacruz, Noelle
  • Emerson, Charlene
  • Farrar, Cassandra
  • Foret, Don
  • Garibay, Edgar
  • Gooch, John
  • Heslop, Michelle
  • Kaur, Sukhjit
  • Khan, Ambreen
  • Kim, Van
  • Lamb, Travis
  • Lindbeck, Peter
  • Lucas, Gabi
  • Macias, Elizabeth
  • Martiniuc, Daniela
  • Mayorga, Lissett
  • Medina, Joseph
  • Membreno, Nelson
  • Messiah, Shady
  • Neufeld, Lacey
  • Nguyen, San Francisco
  • Nichols, Zachary
  • Odisho, George
  • Peterson, Daymon
  • Rodela, Laura
  • Rodriguez, Priscilla
  • Rodriguez, Vanessa
  • Ruiz, Jorge
  • Sherrill, Will
  • Silva, Valeria
  • Sparks, Jeri
  • Statton, Geeta
  • Townsend, Ashley
  • Valdez, Isabel
  • Waters, Mary
  • Westphal, Kyle
  • Winkler, Stacey
  • Zumkehr, Joannee
  • DeJong, Randall J
  • Hoogewerf, Arlene J
  • Ackerman, Cheri M
  • Armistead, Isaac O
  • Baatenburg, Lara
  • Borr, Matthew J
  • Brouwer, Lindsay K
  • Burkhart, Brandon J
  • Bushhouse, Kelsey T
  • Cesko, Lejla
  • Choi, Tiffany YY
  • Cohen, Heather
  • Damsteegt, Amanda M
  • Darusz, Jess M
  • Dauphin, Cory M
  • Davis, Yelena P
  • Diekema, Emily J
  • Drewry, Melissa
  • Eisen, Michelle EM
  • Faber, Hayley M
  • Faber, Katherine J
  • Feenstra, Elizabeth
  • Felzer-Kim, Isabella T
  • Hammond, Brandy L
  • Hendriksma, Jesse
  • Herrold, Milton R
  • Hilbrands, Julia A
  • Howell, Emily J
  • Jelgerhuis, Sarah A
  • Jelsema, Timothy R
  • Johnson, Benjamin K
  • Jones, Kelly K
  • Kim, Anna
  • Kooienga, Ross D
  • Menyes, Erika E
  • Nollet, Eric A
  • Plescher, Brittany E
  • Rios, Lindsay
  • Rose, Jenny L
  • Schepers, Allison J
  • Scott, Geoff
  • Smith, Joshua R
  • Sterling, Allison M
  • Tenney, Jenna C
  • Uitvlugt, Chris
  • VanDyken, Rachel E
  • VanderVennen, Marielle
  • Vue, Samantha
  • Kokan, Nighat P
  • Agbley, Kwabea
  • Boham, Sampson K
  • Broomfield, Daniel
  • Chapman, Kayla
  • Dobbe, Ali
  • Dobbe, Ian
  • Harrington, William
  • Ibrahem, Marwan
  • Kennedy, Andre
  • Koplinsky, Chad A
  • Kubricky, Cassandra
  • Ladzekpo, Danielle
  • Pattison, Claire
  • Ramirez, Roman E
  • Wande, Lucia
  • Woehlke, Sarah
  • Wawersik, Matthew
  • Kiernan, Elizabeth
  • Thompson, Jeffrey S
  • Banker, Roxanne
  • Bartling, Justina R
  • Bhatiya, Chinmoy I
  • Boudoures, Anna L
  • Christiansen, Lena
  • Fosselman, Daniel S
  • French, Kristin M
  • Gill, Ishwar S
  • Havill, Jessen T
  • Johnson, Jaelyn L
  • Keny, Lauren J
  • Kerber, John M
  • Klett, Bethany M
  • Kufel, Christina N
  • May, Francis J
  • Mecoli, Jonathan P
  • Merry, Callie R
  • Meyer, Lauren R
  • Miller, Emily G
  • Mullen, Gregory J
  • Palozola, Katherine C
  • Pfeil, Jacob J
  • Thomas, Jessica G
  • Verbofsky, Evan M
  • Spana, Eric P
  • Agarwalla, Anant
  • Chapman, Julia
  • Chlebina, Ben
  • Chong, Insun
  • Falk, IN
  • Fitzgibbons, John D
  • Friedman, Harrison
  • Ighile, Osagie
  • Kim, Andrew J
  • Knouse, Kristin A
  • Kung, Faith
  • Mammo, Danny
  • Ng, Chun Leung
  • Nikam, Vinayak S
  • Norton, Diana
  • Pham, Philip
  • Polk, Jessica W
  • Prasad, Shreya
  • Rankin, Helen
  • Ratliff, Camille D
  • Scala, Victoria
  • Schwartz, Nicholas U
  • Shuen, Jessica A
  • Xu, Amy
  • Xu, Thomas Q
  • Zhang, Yi
  • Rosenwald, Anne G
  • Burg, Martin G
  • Adams, Stephanie J
  • Baker, Morgan
  • Botsford, Bobbi
  • Brinkley, Briana
  • Brown, Carter
  • Emiah, Shadie
  • Enoch, Erica
  • Gier, Chad
  • Greenwell, Alyson
  • Hoogenboom, Lindsay
  • Matthews, Jordan E
  • McDonald, Mitchell
  • Mercer, Amanda
  • Monsma, Nicholaus
  • Ostby, Kristine
  • Ramic, Alen
  • Shallman, Devon
  • Simon, Matthew
  • Spencer, Eric
  • Tomkins, Trisha
  • Wendland, Pete
  • Wylie, Anna
  • Wolyniak, Michael J
  • Robertson, Gregory M
  • Smith, Samuel I
  • DiAngelo, Justin R
  • Sassu, Eric D
  • Bhalla, Satish C
  • Sharif, Karim A
  • Choeying, Tenzin
  • Macias, Jason S
  • Sanusi, Fareed
  • Torchon, Karvyn
  • Bednarski, April E
  • Alvarez, Consuelo J
  • Davis, Kristen C
  • Dunham, Carrie A
  • Grantham, Alaina J
  • Hare, Amber N
  • Schottler, Jennifer
  • Scott, Zackary W
  • Kuleck, Gary A
  • Yu, Nicole S
  • Kaehler, Marian M
  • Jipp, Jacob
  • Overvoorde, Paul J
  • Shoop, Elizabeth
  • Cyrankowski, Olivia
  • Hoover, Betsy
  • Kusner, Matt
  • Lin, Devry
  • Martinov, Tijana
  • Misch, Jonathan
  • Salzman, Garrett
  • Schiedermayer, Holly
  • Snavely, Michael
  • Zarrasola, Stephanie
  • Parrish, Susan
  • Baker, Atlee
  • Beckett, Alissa
  • Belella, Carissa
  • Bryant, Julie
  • Conrad, Turner
  • Fearnow, Adam
  • Gomez, Carolina
  • Herbstsomer, Robert A
  • Hirsch, Sarah
  • Johnson, Christen
  • Jones, Melissa
  • Kabaso, Rita
  • Lemmon, Eric
  • Vieira, Carolina Marques Dos Santos
  • McFarland, Darryl
  • McLaughlin, Christopher
  • Morgan, Abbie
  • Musokotwane, Sepo
  • Neutzling, William
  • Nietmann, Jana
  • Paluskievicz, Christina
  • Penn, Jessica
  • Peoples, Emily
  • Pozmanter, Caitlin
  • Reed, Emily
  • Rigby, Nichole
  • Schmidt, Lasse
  • Shelton, Micah
  • Shuford, Rebecca
  • Tirasawasdichai, Tiara
  • Undem, Blair
  • Urick, Damian
  • Vondy, Kayla
  • Yarrington, Bryan
  • Eckdahl, Todd T
  • Poet, Jeffrey L
  • Allen, Alica B
  • Anderson, John E
  • Barnett, Jason M
  • Baumgardner, Jordan S
  • Brown, Adam D
  • Carney, Jordan E
  • Chavez, Ramiro A
  • Christgen, Shelbi L
  • Christie, Jordan S
  • Clary, Andrea N
  • Conn, Michel A
  • Cooper, Kristen M
  • Crowley, Matt J
  • Crowley, Samuel T
  • Doty, Jennifer S
  • Dow, Brian A
  • Edwards, Curtis R
  • Elder, Darcie D
  • Fanning, John P
  • Janssen, Bridget M
  • Lambright, Anthony K
  • Lane, Curtiss E
  • Limle, Austin B
  • Mazur, Tammy
  • McCracken, Marly R
  • McDonough, Alexa M
  • Melton, Amy D
  • Minnick, Phillip J
  • Musick, Adam E
  • Newhart, William H
  • Noynaert, Joseph W
  • Ogden, Bradley J
  • Sandusky, Michael W
  • Schmuecker, Samantha M
  • Shipman, Anna L
  • Smith, Anna L
  • Thomsen, Kristen M
  • Unzicker, Matthew R
  • Vernon, William B
  • Winn, Wesley W
  • Woyski, Dustin S
  • Zhu, Xiao
  • Du, Chunguang
  • Ament, Caitlin
  • Aso, Soham
  • Bisogno, Laura Simone
  • Caronna, Jason
  • Fefelova, Nadezhda
  • Lopez, Lenin
  • Malkowitz, Lorraine
  • Marra, Jonathan
  • Menillo, Daniella
  • Obiorah, Ifeanyi
  • Onsarigo, Eric Nyabeta
  • Primus, Shekerah
  • Soos, Mahdi
  • Tare, Archana
  • Zidan, Ameer
  • Jones, Christopher J
  • Aronhalt, Todd
  • Bellush, James M
  • Burke, Christa
  • DeFazio, Steve
  • Does, Benjamin R
  • Johnson, Todd D
  • Keysock, Nicholas
  • Knudsen, Nelson H
  • Messler, James
  • Myirski, Kevin
  • Rekai, Jade Lea
  • Rempe, Ryan Michael
  • Salgado, Michael S
  • Stagaard, Erica
  • Starcher, Justin R
  • Waggoner, Andrew W
  • Yemelyanova, Anastasia K
  • Hark, Amy T
  • Bertolet, Anne
  • Kuschner, Cyrus E
  • Parry, Kesley
  • Quach, Michael
  • Shantzer, Lindsey
  • Shaw, Mary E
  • Smith, Mary A
  • Glenn, Omolara
  • Mason, Portia
  • Williams, Charlotte
  • Key, S Catherine Silver
  • Henry, Tyneshia CP
  • Johnson, Ashlee G
  • White, Jackie X
  • Haberman, Adam
  • Asinof, Sam
  • Drumm, Kelly
  • Freeburg, Trip
  • Safa, Nadia
  • Schultz, Darrin
  • Shevin, Yakov
  • Svoronos, Petros
  • Vuong, Tam
  • Wellinghoff, Jules
  • Hoopes, Laura LM
  • Chau, Kim M
  • Ward, Alyssa
  • Regisford, E Gloria C
  • Augustine, LaJerald
  • Davis-Reyes, Brionna
  • Echendu, Vivienne
  • Hales, Jasmine
  • Ibarra, Sharon
  • Johnson, Lauriaun
  • Ovu, Steven
  • Braverman, John M
  • Bahr, Thomas J
  • Caesar, Nicole M
  • Campana, Christopher
  • Cassidy, Daniel W
  • Cognetti, Peter A
  • English, Johnathan D
  • Fadus, Matthew C
  • Fick, Cameron N
  • Freda, Philip J
  • Hennessy, Bryan M
  • Hockenberger, Kelsey
  • Jones, Jennifer K
  • King, Jessica E
  • Knob, Christopher R
  • Kraftmann, Karen J
  • Li, Linghui
  • Lupey, Lena N
  • Minniti, Carl J
  • Minton, Thomas F
  • Moran, Joseph V
  • Mudumbi, Krishna
  • Nordman, Elizabeth C
  • Puetz, William J
  • Robinson, Lauren M
  • Rose, Thomas J
  • Sweeney, Edward P
  • Timko, Ashley S
  • Paetkau, Don W
  • Eisler, Heather L
  • Aldrup, Megan E
  • Bodenberg, Jessica M
  • Cole, Mara G
  • Deranek, Kelly M
  • DeShetler, Megan
  • Dowd, Rose M
  • Eckardt, Alexandra K
  • Ehret, Sharon C
  • Fese, Jessica
  • Garrett, Amanda D
  • Kammrath, Anna
  • Kappes, Michelle L
  • Light, Morgan R
  • Meier, Anne C
  • O'Rouke, Allison
  • Perella, Mallory
  • Ramsey, Kimberley
  • Ramthun, Jennifer R
  • Reilly, Mary T
  • Robinett, Deirdre
  • Rossi, Nadine L
  • Schueler, Mary Grace
  • Shoemaker, Emma
  • Starkey, Kristin M
  • Vetor, Ashley
  • Vrable, Abby
  • Chandrasekaran, Vidya
  • Beck, Christopher
  • Hatfield, Kristen R
  • Herrick, Douglas A
  • Khoury, Christopher B
  • Lea, Charlotte
  • Louie, Christopher A
  • Lowell, Shannon M
  • Reynolds, Thomas J
  • Schibler, Jeanine
  • Scoma, Alexandra H
  • Smith-Gee, Maxwell T
  • Tuberty, Sarah
  • Smith, Christopher D
  • Lopilato, Jane E
  • Hauke, Jeanette
  • Roecklein-Canfield, Jennifer A
  • Corrielus, Maureen
  • Gilman, Hannah
  • Intriago, Stephanie
  • Maffa, Amanda
  • Rauf, Sabya A
  • Thistle, Katrina
  • Trieu, Melissa
  • Winters, Jenifer
  • Yang, Bib
  • Hauser, Charles R
  • Abusheikh, Tariq
  • Ashrawi, Yara
  • Benitez, Pedro
  • Boudreaux, Lauren R
  • Bourland, Megan
  • Chavez, Miranda
  • Cruz, Samantha
  • Elliott, GiNell
  • Farek, Jesse R
  • Flohr, Sarah
  • Flores, Amanda H
  • Friedrichs, Chelsey
  • Fusco, Zach
  • Goodwin, Zane
  • Helmreich, Eric
  • Kiley, John
  • Knepper, John Mark
  • Langner, Christine
  • Martinez, Megan
  • Mendoza, Carlos
  • Naik, Monal
  • Ochoa, Andrea
  • Ragland, Nicolas
  • Raimey, England
  • Rathore, Sunil
  • Reza, Evangelina
  • Sadovsky, Griffin
  • Seydoux, Marie-Isabelle B
  • Smith, Jonathan E
  • Unruh, Anna K
  • Velasquez, Vicente
  • Wolski, Matthew W
  • Gosser, Yuying
  • Govind, Shubha
  • Clarke-Medley, Nicole
  • Guadron, Leslie
  • Lau, Dawn
  • Lu, Alvin
  • Mazzeo, Cheryl
  • Meghdari, Mariam
  • Ng, Simon
  • Pamnani, Brad
  • Plante, Olivia
  • Shum, Yuki Kwan Wa
  • Song, Roy
  • Johnson, Diana E
  • Abdelnabi, Mai
  • Archambault, Alexi
  • Chamma, Norma
  • Gaur, Shailly
  • Hammett, Deborah
  • Kandahari, Adrese
  • Khayrullina, Guzal
  • Kumar, Sonali
  • Lawrence, Samantha
  • Madden, Nigel
  • Mandelbaum, Max
  • Milnthorp, Heather
  • Mohini, Shiv
  • Patel, Roshni
  • Peacock, Sarah J
  • Perling, Emily
  • Quintana, Amber
  • Rahimi, Michael
  • Ramirez, Kristen
  • Singhal, Rishi
  • Weeks, Corinne
  • Wong, Tiffany
  • Gillis, Aubree T
  • Moore, Zachary D
  • Savell, Christopher D
  • Watson, Reece
  • Mel, Stephanie F
  • Anilkumar, Arjun A
  • Bilinski, Paul
  • Castillo, Rostislav
  • Closser, Michael
  • Cruz, Nathalia M
  • Dai, Tiffany
  • Garbagnati, Giancarlo F
  • Horton, Lanor S
  • Kim, Dongyeon
  • Lau, Joyce H
  • Liu, James Z
  • Mach, Sandy D
  • Phan, Thu A
  • Ren, Yi
  • Stapleton, Kenneth E
  • Strelitz, Jean M
  • Sunjed, Ray
  • Stamm, Joyce
  • Anderson, Morgan C
  • Bonifield, Bethany Grace
  • Coomes, Daniel
  • Dillman, Adam
  • Durchholz, Elaine J
  • Fafara-Thompson, Antoinette E
  • Gross, Meleah J
  • Gygi, Amber M
  • Jackson, Lesley E
  • Johnson, Amy
  • Kocsisova, Zuzana
  • Manghelli, Joshua L
  • McNeil, Kylie
  • Murillo, Michael
  • Naylor, Kierstin L
  • Neely, Jessica
  • Ogawa, Emmy E
  • Rich, Ashley
  • Rogers, Anna
  • Spencer, J Devin
  • Stemler, Kristina M
  • Throm, Allison A
  • Van Camp, Matt
  • Weihbrecht, Katie
  • Wiles, T Aaron
  • Williams, Mallory A
  • Williams, Matthew
  • Zoll, Kyle
  • Bailey, Cheryl
  • Zhou, Leming
  • Balthaser, Darla M
  • Bashiri, Azita
  • Bower, Mindy E
  • Florian, Kayla A
  • Ghavam, Nazanin
  • Greiner-Sosanko, Elizabeth S
  • Karim, Helmet
  • Mullen, Victor W
  • Pelchen, Carly E
  • Yenerall, Paul M
  • Zhang, Jiayu
  • Rubin, Michael R
  • Arias-Mejias, Suzette M
  • Bermudez-Capo, Armando G
  • Bernal-Vega, Gabriela V
  • Colon-Vazquez, Mariela
  • Flores-Vazquez, Arelys
  • Gines-Rosario, Mariela
  • Llavona-Cartagena, Ivan G
  • Martinez-Rodriguez, Javier O
  • Ortiz-Fuentes, Lionel
  • Perez-Colomba, Eliezer O
  • Perez-Otero, Joseph
  • Rivera, Elisandra
  • Rodriguez-Giron, Luke J
  • Santiago-Sanabria, Arnaldo J
  • Senquiz-Gonzalez, Andrea M
  • delValle, Frank R Soto
  • Vargas-Franco, Dorianmarie
  • Velázquez-Soto, Karla I
  • Zambrana-Burgos, Joan D
  • Martinez-Cruzado, Juan Carlos
  • Asencio-Zayas, Lillyann
  • Babilonia-Figueroa, Kevin
  • Beauchamp-Pérez, Francis D
  • Belén-Rodríguez, Juliana
  • Bracero-Quiñones, Luciann
  • Burgos-Bula, Andrea P
  • Collado-Méndez, Xavier A
  • Colón-Cruz, Luis R
  • Correa-Muller, Ana I
  • Crooke-Rosado, Jonathan L
  • Cruz-García, José M
  • Defendini-Ávila, Marianna
  • Delgado-Peraza, Francheska M
  • Feliciano-Cancela, Alex J
  • Gónzalez-Pérez, Valerie M
  • Guiblet, Wilfried
  • Heredia-Negrón, Aldo
  • Hernández-Muñiz, Jennifer
  • Irizarry-González, Lourdes N
  • Laboy-Corales, Ángel L
  • Llaurador-Caraballo, Gabriela A
  • Marín-Maldonado, Frances
  • Marrero-Llerena, Ulises
  • Martell-Martínez, Héctor A
  • Martínez-Traverso, Idaliz M
  • Medina-Ortega, Kiara N
  • Méndez-Castellanos, Sonya G
  • Menéndez-Serrano, Krizia C
  • Morales-Caraballo, Carol I
  • Ortiz-DeChoudens, Saryleine
  • Ortiz-Ortiz, Patricia
  • Pagán-Torres, Hendrick
  • Pérez-Afanador, Diana
  • Quintana-Torres, Enid M
  • Ramírez-Aponte, Edwin G
  • Riascos-Cuero, Carolina
  • Rivera-Llovet, Michelle S
  • Rivera-Pagán, Ingrid T
  • Rivera-Vicéns, Ramón E
  • Robles-Juarbe, Fabiola
  • Rodríguez-Bonilla, Lorraine
  • Rodríguez-Echevarría, Brian O
  • Rodríguez-García, Priscila M
  • Rodríguez-Laboy, Abneris E
  • Rodríguez-Santiago, Susana
  • Rojas-Vargas, Michael L
  • Rubio-Marrero, Eva N
  • Santiago-Colón, Albeliz
  • Santiago-Ortiz, Jorge L
  • Santos-Ramos, Carlos E
  • Serrano-González, Joseline
  • Tamayo-Figueroa, Alina M
  • Tascón-Peñaranda, Edna P
  • Torres-Castillo, José L
  • Valentín-Feliciano, Nelson A
  • Valentín-Feliciano, Yashira M
  • Vargas-Barreto, Nadyan M
  • Vélez-Vázquez, Miguel
  • Vilanova-Vélez, Luis R
  • Zambrana-Echevarría, Cristina
  • MacKinnon, Christy
  • Chung, Hui-Min
  • Kay, Chris
  • Pinto, Anthony
  • Kopp, Olga R
  • Burkhardt, Joshua
  • Harward, Chris
  • Allen, Robert
  • Bhat, Pavan
  • Chang, Jimmy Hsiang-Chun
  • Chen, York
  • Chesley, Christopher
  • Cohn, Dara
  • DuPuis, David
  • Fasano, Michael
  • Fazzio, Nicholas
  • Gavinski, Katherine
  • Gebreyesus, Heran
  • Giarla, Thomas
  • Gostelow, Marcus
  • Greenstein, Rachel
  • Gunasinghe, Hashini
  • Hanson, Casey
  • Hay, Amanda
  • He, Tao Jian
  • Homa, Katie
  • Howe, Ruth
  • Howenstein, Jeff
  • Huang, Henry
  • Khatri, Aaditya
  • Kim, Young Lu
  • Knowles, Olivia
  • Kong, Sarah
  • Krock, Rebecca
  • Kroll, Matt
  • Kuhn, Julia
  • Kwong, Matthew
  • Lee, Brandon
  • Lee, Ryan
  • Levine, Kevin
  • Li, Yedda
  • Liu, Bo
  • Liu, Lucy
  • Liu, Max
  • Lousararian, Adam
  • Ma, Jimmy
  • Mallya, Allyson
  • Manchee, Charlie
  • Marcus, Joseph
  • McDaniel, Stephen
  • Miller, Michelle L
  • Molleston, Jerome M
  • Diez, Cristina Montero
  • Ng, Patrick
  • Ngai, Natalie
  • Nguyen, Hien
  • Nylander, Andrew
  • Pollack, Jason
  • Rastogi, Suchita
  • Reddy, Himabindu
  • Regenold, Nathaniel
  • Sarezky, Jon
  • Schultz, Michael
  • Shim, Jien
  • Skorupa, Tara
  • Smith, Kenneth
  • Spencer, Sarah J
  • Srikanth, Priya
  • Stancu, Gabriel
  • Stein, Andrew P
  • Strother, Marshall
  • Sudmeier, Lisa
  • Sun, Mengyang
  • Sundaram, Varun
  • Tazudeen, Noor
  • Tseng, Alan
  • Tzeng, Albert
  • Venkat, Rohit
  • Venkataram, Sandeep
  • Waldman, Leah
  • Wang, Tracy
  • Yang, Hao
  • Yu, Jack Y
  • Zheng, Yin
  • Preuss, Mary L
  • Garcia, Angelica
  • Juergens, Matt
  • Morris, Robert W
  • Nagengast, Alexis A
  • Azarewicz, Julie
  • Carr, Thomas J
  • Chichearo, Nicole
  • Colgan, Mike
  • Donegan, Megan
  • Gardner, Bob
  • Kolba, Nik
  • Krumm, Janice L
  • Lytle, Stacey
  • MacMillian, Laurell
  • Miller, Mary
  • Montgomery, Andrew
  • Moretti, Alysha
  • Offenbacker, Brittney
  • Polen, Mike
  • Toth, John
  • Woytanowski, John
  • Kadlec, Lisa
  • Crawford, Justin
  • Spratt, Mary L
  • Adams, Ashley L
  • Barnard, Brianna K
  • Cheramie, Martin N
  • Eime, Anne M
  • Golden, Kathryn L
  • Hawkins, Allyson P
  • Hill, Jessica E
  • Kampmeier, Jessica A
  • Kern, Cody D
  • Magnuson, Emily E
  • Miller, Ashley R
  • Morrow, Cody M
  • Peairs, Julia C
  • Pickett, Gentry L
  • Popelka, Sarah A
  • Scott, Alexis J
  • Teepe, Emily J
  • TerMeer, Katie A
  • Watchinski, Carmen A
  • Watson, Lucas A
  • Weber, Rachel E
  • Woodard, Kate A
  • Barnard, Daron C
  • Appiah, Isaac
  • Giddens, Michelle M
  • McNeil, Gerard P
  • Adebayo, Adeola
  • Bagaeva, Kate
  • Chinwong, Justina
  • Dol, Chrystel
  • George, Eunice
  • Haltaufderhyde, Kirk
  • Haye, Joanna
  • Kaur, Manpreet
  • Semon, Max
  • Serjanov, Dmitri
  • Toorie, Anika
  • Wilson, Christopher
  • Riddle, Nicole C
  • Buhler, Jeremy
  • Mardis, Elaine R
  • Elgin, Sarah CR
  • et al.
Abstract

The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties impact the evolution of repeats and genes, we manually improved the sequence and annotated the genes on the D. erecta, D. mojavensis, and D. grimshawi F elements and euchromatic domains from the Muller D element. We find that F elements have greater transposon density (25-50%) than euchromatic reference regions (3-11%). Among the F elements, D. grimshawi has the lowest transposon density (particularly DINE-1: 2% vs. 11-27%). F element genes have larger coding spans, more coding exons, larger introns, and lower codon bias. Comparison of the Effective Number of Codons with the Codon Adaptation Index shows that, in contrast to the other species, codon bias in D. grimshawi F element genes can be attributed primarily to selection instead of mutational biases, suggesting that density and types of transposons affect the degree of local heterochromatin formation. F element genes have lower estimated DNA melting temperatures than D element genes, potentially facilitating transcription through heterochromatin. Most F element genes (~90%) have remained on that element, but the F element has smaller syntenic blocks than genome averages (3.4-3.6 vs. 8.4-8.8 genes per block), indicating greater rates of inversion despite lower rates of recombination. Overall, the F element has maintained characteristics that are distinct from other autosomes in the Drosophila lineage, illuminating the constraints imposed by a heterochromatic milieu.

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