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The Complete Genome Sequence of Haloferax volcanii DS2, a Model Archaeon
- Hartman, Amber L;
- Norais, Cédric;
- Badger, Jonathan H;
- Delmas, Stéphane;
- Haldenby, Sam;
- Madupu, Ramana;
- Robinson, Jeffrey;
- Khouri, Hoda;
- Ren, Qinghu;
- Lowe, Todd M;
- Maupin-Furlow, Julie;
- Pohlschroder, Mecky;
- Daniels, Charles;
- Pfeiffer, Friedhelm;
- Allers, Thorsten;
- Eisen, Jonathan A
- Editor(s): Friedberg, Iddo
- et al.
Published Web Location
https://doi.org/10.1371/journal.pone.0009605Abstract
Background
Haloferax volcanii is an easily culturable moderate halophile that grows on simple defined media, is readily transformable, and has a relatively stable genome. This, in combination with its biochemical and genetic tractability, has made Hfx. volcanii a key model organism, not only for the study of halophilicity, but also for archaeal biology in general.Methodology/principal findings
We report here the sequencing and analysis of the genome of Hfx. volcanii DS2, the type strain of this species. The genome contains a main 2.848 Mb chromosome, three smaller chromosomes pHV1, 3, 4 (85, 438, 636 kb, respectively) and the pHV2 plasmid (6.4 kb).Conclusions/significance
The completed genome sequence, presented here, provides an invaluable tool for further in vivo and in vitro studies of Hfx. volcanii.Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.
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