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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.

  • Author(s): Perera, Rushika
  • Son, J
  • Lyssiotis, CA
  • Ying, H
  • Wang, X
  • Hua, S
  • Ligorio, M
  • Perera, RM
  • Ferrone, CR
  • Mullarky, E
  • Shyh-Chang, N
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3656466?pdf=render
No data is associated with this publication.
Abstract

Cancer cells have metabolic dependencies that distinguish them from their normal counterparts. Among these dependencies is an increased use of the amino acid glutamine to fuel anabolic processes. Indeed, the spectrum of glutamine-dependent tumours and the

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