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PD-1 modulates steady-state and infection-induced IL-10 production in vivo

  • Author(s): Herbert, Debroski
  • Mcberry, C
  • Dias, A
  • Shryock, N
  • Lampe, K
  • Gutierrez, FRS
  • Boon, L
  • Herbert, DR
  • Aliberti, J
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3955717?pdf=render
No data is associated with this publication.
Abstract

Programmed death-1 (PD-1) plays an important role in mediating immune tolerance through mechanisms that remain unclear. Herein, we investigated whether PD-1 prevents excessive host tissue damage during infection with the protozoan parasite, Toxoplasma gond

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