Skip to main content
eScholarship
Open Access Publications from the University of California

Argonaute and Argonaute-Bound Small RNAs in Stem Cells.

  • Author(s): Zhai, Lihong
  • Wang, Lin
  • Teng, Feng
  • Zhou, Lanting
  • Zhang, Wenjing
  • Xiao, Juan
  • Liu, Ying
  • Deng, Wenbin
  • et al.
Abstract

Small RNAs are essential for a variety of cellular functions. Argonaute (AGO) proteins are associated with all of the different classes of small RNAs, and are indispensable in small RNA-mediated regulatory pathways. AGO proteins have been identified in various types of stem cells in diverse species from plants and animals. This review article highlights recent progress on how AGO proteins and AGO-bound small RNAs regulate the self-renewal and differentiation of distinct stem cell types, including pluripotent, germline, somatic, and cancer stem cells.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content
Current View