Skip to main content
Download PDF
- Main
An endocannabinoid mechanism for stress-induced analgesia
- Hohmann, Andrea G;
- Suplita, Richard L;
- Bolton, Nathan M;
- Neely, Mark H;
- Fegley, Darren;
- Mangieri, Regina;
- Krey, Jocelyn F;
- Michael Walker, J;
- Holmes, Philip V;
- Crystal, Jonathon D;
- Duranti, Andrea;
- Tontini, Andrea;
- Mor, Marco;
- Tarzia, Giorgio;
- Piomelli, Daniele
Published Web Location
https://doi.org/10.1038/nature03658Abstract
Stress cancellingStress activates the neural systems that inhibit the sensation of pain, inducing natural analgesia. Some of these pathways involve natural opiates but now an endocannabinoid-based equivalent has been found. The enzymes that break up these natural marijuana-like compounds may be important therapeutic targets for stress-related disorders.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.