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Open Access Publications from the University of California

Dimethyl Fumarate Ameliorates Acute Pancreatitis in Rodent

  • Author(s): Robles, L
  • Vaziri, ND
  • Li, S
  • Takasu, C
  • Masuda, Y
  • Vo, K
  • Farzaneh, SH
  • Stamos, MJ
  • Ichii, H
  • et al.

OBJECTIVES: Pancreatitis is a complex inflammatory disorder, ranging from a mild attack, to severe and potentially fatal condition. Dimethyl fumarate (DMF), a potent antioxidant and anti-inflammatory, has been used medicinally for decades. The purpose of this study was to test the hypothesis that treatment with DMF may ameliorate acute pancreatitis (AP) in a rodent model.

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