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DNA unwinding heterogeneity by RecBCD results from static molecules able to equilibrate
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https://doi.org/10.1038/nature12333Abstract
The bacterial RecBCD helicase/nuclease shows broad, and apparently static, heterogeneity in the unwinding rate manifest by individual molecules: here it is shown that transiently halting an enzyme during processive translocation allows for a change, most likely conformational, such that the velocity of the molecule after pausing can fall anywhere within the spectrum of rates seen for a population.
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