Profiling solute carrier transporters in the human blood-brain barrier
- Author(s): Giacomini, Kathleen
- Geier, EG
- Chen, EC
- Webb, A
- Papp, AC
- Yee, SW
- Sadee, W
- Giacomini, KM
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3906042?pdf=render
The neuroprotective function of the blood-brain barrier (BBB) presents a major challenge for drug delivery to the central nervous system (CNS). Critical to this function, BBB membrane transporters include the ATP-binding cassette (ABC) transporters, which
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