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Functional and Histologic Analysis of a Novel Elastic Biodegradable Patch for CDH Repair
- Theodorou, Christina M;
- Taylor, Alan;
- Lee, Su Yeon;
- Fu, Huikang;
- Pivetti, Christopher D;
- Zhang, Chaoxing;
- Stasyuk, Anastasiya;
- Hao, Dake;
- Kumar, Priyadarsini;
- Farmer, Diana L;
- Liao, Jun;
- Brown, Erin G;
- Hong, Yi;
- Wang, Aijun
The data associated with this publication are not available for this reason: N/A
Abstract
CDH is a congenital defect in the diaphragm causing herniation of abdominal contents and impaired lung growth. PTFE is a synthetic polymer that is the current standard of care for patch repair of CDH. Limitations: stiff, not biodegradable, no growth with the child leading to reherniation and repeated intervention. Polyurethane (PU) is a novel material that is elastic, biodegradable, and biocompatible, allowing for optimized lung mechanics and tissue integration.