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Placental Mesenchymal Stem Cells Improve Motor Function in a Rat Unilateral Spinal Cord Contusion Model
- Mor, Sirjan;
- Kulubya, Edwin;
- Bhaskara, Mounika;
- Paxton, Zachory;
- Kumar, Priyadarsini;
- Pivetti, Chris;
- Avallone, Samantha;
- Wang, Aijun;
- Farmer, Diana
The data associated with this publication are not available for this reason: N/A
Abstract
Spinal cord injuries (SCI) are devastating with no effective treatments and excessive medical costs. Placental mesenchymal stem cells (PMSCs) are a promising avenue of treatment due to their neuroprotective and angiogenic properties (Kumar, 2019). In addition, extracellular vesicles (EVs) released from these stem cells are an attractive cell-free therapeutic approach. Extracellular vesicles are approximately 150 nm vesicles released by placental mesenchymal stem cells that contain the proteins, miRNAs and other cargo of the cells themselves (Ramasubramanian 2019).