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Six-year contraceptive efficacy and continued safety of a levonorgestrel 52 mg intrauterine system
Published Web Location
https://doi.org/10.1016/j.contraception.2019.10.010Abstract
Objective
To assess 6-year contraceptive efficacy and safety of a levonorgestrel 52 mg intrauterine system (IUS).Study design
We assessed pregnancy rates through 72 months in women aged 16-35 years at enrollment and safety in all participants (aged 16-45 years, n = 1751) in an ongoing 10-year phase-3 trial.Results
Over six years, nine pregnancies occurred (none in year 6) for a life-table pregnancy rate of 0.87 (95% CI 0.44-1.70). Adverse event rates remain low through 6 or more years of use. Two expulsions occurred in year 6.Conclusion
This levonorgestrel 52 mg IUS is a highly effective and safe contraceptive over 6 years of use.Implications
The levonorgestrel 52 mg IUS shows high 6-year contraceptive efficacy and a low rate of adverse events through 6 or more years of use.Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.
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