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The metastasis associated protein S100A4: role in tumour progression and metastasis.

  • Author(s): Helfman, DM
  • Kim, EJ
  • Lukanidin, E
  • Grigorian, M
  • et al.
Abstract

The metastasis associated protein S100A4 is a small calcium binding protein that is associated with metastatic tumors and appears to be a molecular marker for clinical prognosis. Below we discuss its biochemical properties and possible cellular functions in metastasis including cell motility, invasion, apoptosis, angiogenesis and differentiation.

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