The metastasis associated protein S100A4: role in tumour progression and metastasis.
- Author(s): Helfman, DM
- Kim, EJ
- Lukanidin, E
- Grigorian, M
- et al.
Published Web Locationhttps://doi.org/10.1038/sj.bjc.6602613
The metastasis associated protein S100A4 is a small calcium binding protein that is associated with metastatic tumors and appears to be a molecular marker for clinical prognosis. Below we discuss its biochemical properties and possible cellular functions in metastasis including cell motility, invasion, apoptosis, angiogenesis and differentiation.