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A Novel Shiga Toxin 1a-Converting Bacteriophage of Shigella sonnei With Close Relationship to Shiga Toxin 2-Converting Pages of Escherichia coli.

  • Author(s): Carter, Christoph C;
  • Fierer, Joshua;
  • Chiu, Wei Wei;
  • Looney, David J;
  • Strain, Matthew;
  • Mehta, Sanjay R
  • et al.
Abstract

In recent studies, strains of non-dysenteriae 1 Shigella (NDS) expressing Shiga toxin have been reported. In this study, we report a novel stx1a-converting bacteriophage of Shigella sonnei associated with travel to Mexico. Phylogenetic comparison between this and other stx-converting phages suggests that toxigenic NDS strains have arisen through separate horizontal transfer events from toxigenic Escherichia coli.

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