UC San Diego
A Novel Shiga Toxin 1a-Converting Bacteriophage of Shigella sonnei With Close Relationship to Shiga Toxin 2-Converting Pages of Escherichia coli.
- Author(s): Carter, Christoph C
- Fierer, Joshua
- Chiu, Wei Wei
- Looney, David J
- Strain, Matthew
- Mehta, Sanjay R
- et al.
Published Web Locationhttps://doi.org/10.1093/ofid/ofw079
In recent studies, strains of non-dysenteriae 1 Shigella (NDS) expressing Shiga toxin have been reported. In this study, we report a novel stx1a-converting bacteriophage of Shigella sonnei associated with travel to Mexico. Phylogenetic comparison between this and other stx-converting phages suggests that toxigenic NDS strains have arisen through separate horizontal transfer events from toxigenic Escherichia coli.