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Metabolic reprogramming in mutant IDH1 glioma cells

  • Author(s): Pieper, Russell
  • Phillips, Joanna
  • Ronen, Sabrina
  • Izquierdo-Garcia, JL
  • Viswanath, P
  • Eriksson, P
  • Chaumeil, MM
  • Pieper, RO
  • Phillips, JJ
  • Ronen, SM
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4338038?pdf=render
No data is associated with this publication.
Abstract

© 2015 Izquierdo-Garcia et al.Background: Mutations in isocitrate dehydrogenase (IDH) 1 have been reported in over 70% of low-grade gliomas and secondary glioblastomas. IDH1 is the enzyme that catalyzes the oxidative decarboxylation of isocitrate to α-keto

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