GBZ-base and GAF-base: Indexed pangenome file formats.
Published Web Location
https://doi.org/10.64898/2026.07.10.737775
Abstract
MOTIVATION: Existing pangenome file formats are designed for batch processing. Graphs must be loaded into memory, and alignment files must be read sequentially. Indexed file formats that can be used directly from disk would be more appropriate for interactive applications. RESULTS: We propose GBZ-base and GAF-base - SQLite-backed file formats comparable to GBZ and GAF. GBZ-base supports efficient extraction of local subgraphs, and GAF-base lets us extract all alignments to the subgraph. Additionally, GAF-base is smaller than any other file format for sequence-to-graph alignments. AVAILABILITY AND IMPLEMENTATION: From https://github.com/jltsiren/gbz-base and https://crates.io/crates/gbz-base under the MIT license.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.