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Multifunctional and Scalable Nanoparticles for Bimodal Image-Guided Phototherapy in Bladder Cancer Treatment
- Tang, Menghuan;
- Mahri, Sohaib;
- Shiau, Ya-Ping;
- Mukarrama, Tasneem;
- Villa, Rodolfo;
- Zong, Qiufang;
- Racacho, Kelsey Jane;
- Li, Yangxiong;
- Lee, Yunyoung;
- Huang, Yanyu;
- Cong, Zhaoqing;
- Kim, Jinhwan;
- Li, Yuanpei;
- Lin, Tzu-Yin
Published Web Location
https://doi.org/10.1007/s40820-025-01717-0Abstract
HighlightsPyropheophorbide a–bisaminoquinoline conjugate lipid nanoparticles (PPBC LNPs), formulated with lipid-based excipients and assembled using microfluidics, exhibit excellent biocompatibility and stability, indicating promise for clinical applications.PPBC LNPs possess remarkable photoacoustic and fluorescence imaging capabilities, enabling high-resolution, deep tissue penetration and high sensitivity imaging for tracking drug biodistribution and phototherapy efficacy.
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