Skip to main content
Open Access Publications from the University of California

Heterotrimeric G Protein-coupled Receptor Signaling in Yeast Mating Pheromone Response.

  • Author(s): Alvaro, Christopher G
  • Thorner, Jeremy
  • et al.

The DNAs encoding the receptors that respond to the peptide mating pheromones of the budding yeastSaccharomyces cerevisiaewere isolated in 1985, and were the very first genes for agonist-binding heterotrimeric G protein-coupled receptors (GPCRs) to be cloned in any organism. Now, over 30 years later, this yeast and its receptors continue to provide a pathfinding experimental paradigm for investigating GPCR-initiated signaling and its regulation, as described in this retrospective overview.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content
Current View