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Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function

  • Author(s): Jacobson, Matthew
  • Babbitt, Patricia
  • Kim, J
  • Xiao, H
  • Bonanno, JB
  • Kalyanaraman, C
  • Brown, S
  • Tang, X
  • Al-Obaidi, NF
  • Patskovsky, Y
  • Babbitt, PC
  • Jacobson, MP
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3895326?pdf=render
No data is associated with this publication.
Abstract

The identification of novel metabolites and the characterization of their biological functions are major challenges in biology. X-ray crystallography can reveal unanticipated ligands that persist through purification and crystallization. These adventitious

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