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Pain Facilitation Brain Regions Activated by Nalbuphine Are Revealed by Pharmacological fMRI
Published Web Location
http://europepmc.org/articles/PMC3540048?pdf=renderNo data is associated with this publication.
Abstract
Nalbuphine, an agonist-antagonist kappa-opioid, produces brief analgesia followed by enhanced pain/hyperalgesia in male postsurgical patients. However, it produces profound analgesia without pain enhancement when co-administration with low dose naloxone. T
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