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Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells
Published Web Location
http://europepmc.org/articles/PMC3893718?pdf=renderNo data is associated with this publication.
Abstract
DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA demethylation occurs in the early embryo and the germ line, and may be mediated by Tet (ten eleven translocat
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