Chronic hyponatremia and association with osteoporosis among a large racially/ethnically diverse population
Published Web Locationhttps://doi.org/10.1007/s00198-018-04832-4
Chronic hyponatremia may contribute to decreased bone density. We studied 341,003 men and women who underwent DXA testing and observed that individuals with chronic hyponatremia (sodium < 135 mEq/L) had an 11% greater likelihood of having osteoporosis. There was a dose-dependent effect with lower sodium and stronger association with osteoporosis.