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SIRT1 deacetylates RORγt and enhances Th17 cell generation

  • Author(s): Ott, Melanie
  • Akassoglou, Aikaterini
  • Verdin, Eric
  • Lim, HW
  • Kang, SG
  • Ryu, JK
  • Schilling, B
  • Fei, M
  • Lee, IS
  • Kehasse, A
  • Shirakawa, K
  • Yokoyama, M
  • Schnölzer, M
  • et al.

Published Web Location

http://europepmc.org/articles/PMC4419343?pdf=render
No data is associated with this publication.
Abstract

© 2015 Lim et al.The balance of effector and regulatory T cell function, dependent on multiple signals and epigenetic regulators, is critical to immune self-tolerance. Dysregulation of T helper 17 (Th17) effector cells is associated with multiple autoimmun

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