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SIRT1 deacetylates RORγt and enhances Th17 cell generation

Published Web Location

http://europepmc.org/articles/PMC4419343?pdf=render
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Abstract

© 2015 Lim et al.The balance of effector and regulatory T cell function, dependent on multiple signals and epigenetic regulators, is critical to immune self-tolerance. Dysregulation of T helper 17 (Th17) effector cells is associated with multiple autoimmun

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