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Interferon‐Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non‐human primates
- Yee, JoAnn L;
- Prongay, Kamm;
- Miles, Brodie;
- Smedley, Jeremy;
- Hansen, Scott G;
- Axthelm, Michael K;
- Ardeshir, Amir;
- Van Rompay, Koen KA;
- Timmel, Gregory;
- Roberts, Jeffrey A
Published Web Location
https://doi.org/10.1111/jmp.12420Abstract
We have formatted an assay to detect Mycobacterium tuberculosis complex infections of non-human primates. Commercially available reagents were used to elicit a specific immune response that was measured by interferon-gamma release. Initial evaluation using blood samples from Rhesus macaques experimentally infected with M tuberculosis distinguished infected versus uninfected animals.
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