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Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis
- Gestwicki, Jason;
- Selenica, MLB;
- Davtyan, H;
- Housley, SB;
- Blair, LJ;
- Gillies, A;
- Nordhues, BA;
- Zhang, B;
- Liu, J;
- Gestwicki, JE;
- Lee, DC
Published Web Location
http://europepmc.org/articles/PMC4167523?pdf=renderNo data is associated with this publication.
Abstract
© 2014 Selenica et al.; licensee BioMed Central Ltd.Background: Abnormal tau hyperphosphorylation and its accumulation into intra-neuronal neurofibrillary tangles are linked to neurodegeneration in Alzheimer's disease and similar tauopathies. One strategy
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