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Recon3D enables a three-dimensional view of gene variation in human metabolism
- Brunk, Elizabeth;
- Sahoo, Swagatika;
- Zielinski, Daniel C;
- Altunkaya, Ali;
- Dräger, Andreas;
- Mih, Nathan;
- Gatto, Francesco;
- Nilsson, Avlant;
- Preciat Gonzalez, German Andres;
- Aurich, Maike Kathrin;
- Prlić, Andreas;
- Sastry, Anand;
- Danielsdottir, Anna D;
- Heinken, Almut;
- Noronha, Alberto;
- Rose, Peter W;
- Burley, Stephen K;
- Fleming, Ronan MT;
- Nielsen, Jens;
- Thiele, Ines;
- Palsson, Bernhard O
Published Web Location
https://doi.org/10.1038/nbt.4072Abstract
Large-scale integration of metabolite and protein structural data with existing networks of human metabolism provides insights into gene function and how drugs affect metabolic response.
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