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Improved human islet preparations using glucocorticoid and exendin-4
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https://doi.org/10.1097/MPA.0000000000000184Abstract
Objectives: The effects of glucocorticoid during culture on human islet cells have been controversial. Exendin-4 (EX) enhances the insulin secretion and significantly improves clinical outcomes in islet cell transplantation. In this study, we examined the effects of glucocorticoids and EX on human islet cells during pretransplant culture.
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