Hydrogen Bonding between Solutes in Solvents Octan-1-ol and Water
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Hydrogen Bonding between Solutes in Solvents Octan-1-ol and Water

  • Author(s): Abraham, Michael H
  • Gola, Joelle M. R
  • Cometto-Muniz, J. Enrique
  • Acree, William E
  • et al.

Published Web Location

https://doi.org/10.1021/jo1014646
The data associated with this publication are within the manuscript.
Abstract

1:1 Equilibrium constants, K, for the association of hydrogen bond bases and hydrogen bond acids have been determined using solvent octan-1-ol at 298 K for 30 acid-base combinations. The values of K are much smaller than those found for aprotic, rather non-polar solvents. It is shown that the log K values can satisfactorily be correlated against aH 2*bH 2, where aH 2 and bH 2are the 1:1 hydrogen bond acidities and basicities of solutes. The slope of the plot, 2.938, is much smaller than those for log K values in the non-polar organic solvents previously studied. An analysis of literature data on 1:1 hydrogen bonding in water yields a negative slope for a plot of log K against aH 2*bH 2, thus showing how the use of very strong hydrogen bond acids and bases                                                 does not lead to larger values of log K for 1:1 hydrogen bonding in water. It is suggested that for simple 1:1 association between mono-functional solutes in water, log K cannot be larger than about -0.1 log units. Descriptors have been obtained for the complex between 2,2,2-trifluoroethanol and propanone, and used to analyze solvent effects on the two reactants, the complex, and the complexation constant.

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