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Learning enhances the relative impact of top-down processing in the visual cortex

Abstract

By examining the activity of layer 2/3 excitatory neurons in the mouse primary visual cortex, the authors demonstrate that learning enhances the relative impact of top-down processing by the retrosplenial cortex while reducing the influence of the bottom-up stream from layer 4 excitatory neurons. This effect is partially mediated by somatostatin-expressing inhibitory neurons.

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