Comprehensive Annotation of Mature Peptides and Genotypes for Zika Virus.
- Author(s): Sun, Guangyu
- Larsen, Christopher N
- Baumgarth, Nicole
- Klem, Edward B
- Scheuermann, Richard H
- et al.
Published Web Locationhttps://doi.org/10.1371/journal.pone.0170462
The rapid spread of Zika virus (ZIKV) has caused much concern in the global health community, due in part to a link to fetal microcephaly and other neurological illnesses. While an increasing amount of ZIKV genomic sequence data is being generated, an understanding of the virus molecular biology is still greatly lacking. A significant step towards establishing ZIKV proteomics would be the compilation of all proteins produced by the virus, and the resultant virus genotypes. Here we report for the first time such data, using new computational methods for the annotation of mature peptide proteins, genotypes, and recombination events for all ZIKV genomes. The data is made publicly available through the Virus Pathogen Resource at www.viprbrc.org.