Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation
Abstract
This article contains errors in the Introduction, where “AppNL-G-F/NL-G-F mice carrying the homozygous mutant App gene encoding the humanised Aβ sequence (G601R, F606Y, and R609H) with three pathogenic mutations, namely Swedish (KM595/596NL), Beyreuther/Iberian (I641F), and Arctic (E618G)10, progressively exhibit Aβ accumulation starting at 4 to 6 months of age, dense distributions of microglia and astrocytes from 9 months of age, and behavioural symptoms from 8 to 12 months of age10,11.” should read: “AppNL-G-F/NL-G-F mice carrying the homozygous mutant App gene encoding the humanised Aβ sequence (G676R, F681Y, and R684H) with three pathogenic mutations, namely Swedish (KM670/671NL), Beyreuther/Iberian (I716F), and Arctic (E693G)10, progressively exhibit Aβ accumulation starting at 4 to 6 months of age, dense distributions of microglia and astrocytes from 9 months of age, and behavioural symptoms from 8 to 12 months of age10,11.” In addition, in the Methods section, under the subheading ‘Animals’, “Heterozygous App+/NL-G-F mice carrying humanised Aβ sequence (G601R, F606Y, R609H), Swedish (ML595/596NL), Beyreuther/Iberian (I641F), and Arctic (E618G) mutations, were previously established10.” should read: “Heterozygous App+/NL-G-F mice carrying humanised Aβ sequence (G676R, F681Y, R684H), Swedish (KM670/671NL), Beyreuther/Iberian (I716F), and Arctic (E693G) mutations, were previously established10.”
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