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Colloidal drug formulations can explain "bell-shaped" concentration-response curves

Published Web Location

http://europepmc.org/articles/PMC3985758?pdf=render
No data is associated with this publication.
Abstract

Drug efficacy does not always increase sigmoidally with concentration, which has puzzled the community for decades. Unlike standard sigmoidal curves, bell-shaped concentration-response curves suggest more complex biological effects, such as multiple-bindin

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