Shedding light on local kinase activation
Published Web Locationhttp://dx.doi.org/10.1186/1741-7007-10-61
Abstract Phosphorylation is the predominant language of cell signaling. And, as with any common language, an abundance of dialects has evolved to convey complex information. We discuss here how biosensors are being used to decode this language, affording an unprecedented glimpse into spatio-temporal patterns of protein phosphorylation events within the cell.