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Lipopolysaccharide O-antigen delays plant innate immune recognition of Xylella fastidiosa.

  • Author(s): Rapicavoli, Jeannette N
  • Blanco-Ulate, Barbara
  • Muszyński, Artur
  • Figueroa-Balderas, Rosa
  • Morales-Cruz, Abraham
  • Azadi, Parastoo
  • Dobruchowska, Justyna M
  • Castro, Claudia
  • Cantu, Dario
  • Roper, M Caroline
  • et al.
Abstract

Lipopolysaccharides (LPS) are among the known pathogen-associated molecular patterns (PAMPs). LPSs are potent elicitors of PAMP-triggered immunity (PTI), and bacteria have evolved intricate mechanisms to dampen PTI. Here we demonstrate that Xylella fastidiosa (Xf), a hemibiotrophic plant pathogenic bacterium, possesses a long chain O-antigen that enables it to delay initial plant recognition, thereby allowing it to effectively skirt initial elicitation of innate immunity and establish itself in the host. Lack of the O-antigen modifies plant perception of Xf and enables elicitation of hallmarks of PTI, such as ROS production specifically in the plant xylem tissue compartment, a tissue not traditionally considered a spatial location of PTI. To explore translational applications of our findings, we demonstrate that pre-treatment of plants with Xf LPS primes grapevine defenses to confer tolerance to Xf challenge.

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