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GLP-1 acts on habenular avoidance circuits to control nicotine intake

Creative Commons 'BY' version 4.0 license
Abstract

Nicotine has rewarding effects that motivate its consumption. In addition to these rewarding effects, nicotine also has aversive properties that motivate its avoidance. Here the authors identify a pathway in the brain that regulates nicotine avoidance. Adaptive responses in this and other aversion-related pathways may contribute to the development of tobacco addiction.

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