Skip to main content
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles
Published Web Location
http://europepmc.org/articles/PMC3657615?pdf=renderNo data is associated with this publication.
Abstract
Targeting noncatalytic cysteine residues with irreversible acrylamide-based inhibitors is a powerful approach for enhancing pharmacological potency and selectivity. Nevertheless, concerns about off-target modification motivate the development of reversible
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.