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Determination of receptor specificities for whole influenza viruses using multivalent glycan arrays
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https://doi.org/10.1039/c4cc08613aAbstract
Influenza viruses bind to mucosal glycans to gain entry into a host organism and initiate infection. The target glycans are often displayed in multivalent arrangements on proteins; however, how glycan presentation influences viral specificity is poorly understood. Here, we report a microarray platform approximating native glycan display to facilitate such studies.
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