This paper outlines a research agenda that addresses the question of how contemporary interactive arts practice can evolve new strategies or ways of facilitating the development of subjective experiences that elicit an embodied, felt sense and awareness of our co-evolution with intelligent systems and digital technologies. Drawing upon and extending a phenomenological model of intentionality, we introduce the concept of the “symbiogenic experience” in relation to interactive or technologically-mediated artworks and discuss early research explorations that exemplify it.

Con este artículo se busca precisar algunas de las convencionalidades interpretativas que se identificaron durante el montaje de 6 piezas para guitarra solista del maestro Gentil Montaña escritas en ritmo de bambuco (de sus 5 Suites y la primera de sus 3 Fantasías), con el fin de compartir algunas de las visiones estéticas que tuvo el compositor para con el género y trazando una línea guía que pueda funcionar para una interpretación que convenga a cada una de las piezas teniendo en cuenta los diferentes tipos de bambuco que se pudieron observar durante el trabajo y, por supuesto, los gestos propios del compositor. Debido a que los intentos por mejorar cualquier interpretación de música folclórica se quedarían cortos sin un acercamiento directo con la cultura de la cual proviene, en este trabajo se buscan las diferencias existentes dentro del grupo de piezas, según gestos enmarcados en subgéneros que tienen que ver con la ubicación geográfica, época e influencias, en los que se pudo inspirar el compositor para la escritura del bambuco en guitarra solista.

Dendritic cells (DCs) are critical for the differentiation and activation of type 2 T helper (Th2) cells, which provide protection from parasitic worm infections, yet also aggravate inflammation as seen in asthma and other allergic diseases. Yet little is known concerning the mechanisms employed by DCs to induce Th2 cells in the draining lymph node (LN) or to sustain activation of the T cells in the tissue during ongoing inflammation. In the lymph node, we show that DC induction of Th2 cells depends on the MARCH1 ubiquitin ligase. This pro-Th2 effect of MARCH1 relied on LN-resident DCs, which triggered T cell receptor (TCR) signalling and induced GATA-3 expression from naïve CD4+ T cells independent of tissue-driven migratory DCs. Mice with mutations in the ubiquitin acceptor sites of the antigen presenting molecule MHCII and costimulatory ligand CD86, the substrates of MARCH1, failed to develop Th2 cells. In the allergen-exposed tissue, we also found that MARCH1 in DCs played an essential role in sustaining effector CD4+ T cells. MARCH1-mediated turnover of MHCII and CD86 restrained exhaustion of effector CD4+ T cells, permissive with the robust proliferation of the T cells and the establishment of allergic inflammation. MARCH1 ablation in mice with established asthma reduced tissue infiltration of disease-associated eosinophils and Th2 cells. Thus, Th2 cell development and function in the lymph node and tissue depend on MARCH1-mediated turnover of antigen presenting and costimulatory molecules by DCs to control TCR signalling and T cell exhaustion. MARCH1 may serve as a novel therapeutic target in asthma and other allergic diseases.

America has a rich history of rail transit investments shaping the form and character of cities and regions. Classic works by Warner (1962), Vance (1964), and Fogelson (1967) chronicled how the extension of electric streetcar lines around the turn-of-the-century led to massive decentralization and the emergence of "streetcar suburbs" in Boston, the San Francisco Bay Area, and Southern California. Many east coast cities today stand as testaments to rail transit's city-shaping abilities.

This ethnographic case study employed a person-centered approach to explore the experiences of a Latinx family navigating an elite, predominantly White independent school in Los Angeles. The study aimed to examine how individual and collective identity development were shaped by these experiences, utilizing Yosso’s (2005) Community Cultural Wealth theory, Crenshaw’s (1991) concept of intersectionality, and a person-centered ethnographic method. These strength-based frameworks provided a nuanced understanding of Latinx families beyond the stereotypes often present in such school environments.

The participant family, selected purposefully, consists of two immigrant parents (from Mexico and El Salvador) and their four daughters, who have navigated the independent school from 2016 to now. Together, they offered nearly a decade of insights into navigating the independent school system as a first-generation, lower-income Latinx family. The study employed a methodologically rich design influenced by Critical Race Feminista Methodology. The 22 interviews conducted included family interviews, education journey mapping, walking interviews, artifact-driven interviews, and member check interviews. The first research question that guided the study focused on how each member of the Latinx family unit made sense of their educational journey and what they learned along the way. The second research question focused on how each Latinx family member made sense of their overall experience at a Los Angeles elite, predominantly White independent school. The findings underscore the Latinx family’s resilience and adaptability amid systemic and cultural challenges. Parents’ consistent support and sisters’ varied emotional and practical help shaped the daughters’ success. Findings about their time at the independent school revealed issues such as microaggressions related to race, class, and gender, inequities in academic placement, and college counseling shortcomings. These challenges, cultural negotiation, and first-generation college barriers deeply affected their identity development. Ultimately, the family concluded that the benefits of independent school education outweighed its difficulties. This study offers L.A.-area independent schools valuable insights to serve first-generation, lower-income Latinx families better while contributing to the limited research on the role of independent schools in fostering or hindering non-dominant forms of capital.

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