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Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit
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https://doi.org/10.1038/nature16161Abstract
Epithelial tuft cells are shown to be the source of intestinal interleukin (IL)-25 that is required for activation of type 2 innate lymphoid cells (ILC2s), ILC2-regulated tuft and goblet cell expansion, and control of parasite infection.
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