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Cerebral Organoids in a Dish: Progress and Prospects
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https://doi.org/10.1016/j.cell.2013.09.010Abstract
A three-dimensional culture of cortical tissues derived from pluripotent stem cells offers an opportunity to model human brain development and disorders. In a recent issue of Nature, Lancaster et al. describe a new method for generating cerebral organoids in a dish and use it to model microcephaly.
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