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Optical Coherence Tomography of Malignancies of the Head and Neck


Optical coherence tomography (OCT) is a minimally invasive optical imaging modality which produces high-resolution, three-dimensional (3D) images of biological tissue. In the last 10 years, biophotonics and optics research have led to the advancement of OCT technology and expansion of OCT applications within Otorhinolaryngology-Head and Neck Surgery. In vivo clinical studies have demonstrated the potential for OCT to perform minimally invasive diagnostic imaging and differentiation of premalignant and malignant lesions of the head and neck. This chapter reviews the research and clinical applications for OCT imaging of malignancy in the upper aerodigestive tract.

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