Skip to main content
Download PDF
- Main
CaMKII phosphorylation of neuroligin-1 regulates excitatory synapses
- Bemben, Michael A;
- Shipman, Seth L;
- Hirai, Takaaki;
- Herring, Bruce E;
- Li, Yan;
- Badger, John D;
- Nicoll, Roger A;
- Diamond, Jeffrey S;
- Roche, Katherine W
Published Web Location
https://doi.org/10.1038/nn.3601Abstract
This study shows that neuroligin-1, a trans-synaptic cell adhesion molecule for excitatory synapses, is directly phosphorylated by Ca2+/CaM kinase II in a neuronal activity–dependent manner in vitro and in vivo. The authors also show that this post-translational modification of neuroligin-1 regulates excitatory synaptic potentiation.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.