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Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome

  • Author(s): Grissom, CK
  • Hirshberg, EL
  • Dickerson, JB
  • Brown, SM
  • Lanspa, MJ
  • Liu, KD
  • Schoenfeld, D
  • Tidswell, M
  • Hite, RD
  • Rock, P
  • Miller, RR
  • Morris, AH
  • Hudson, L
  • Gundel, S
  • Hough, C
  • Neff, M
  • Sims, K
  • Ungar, A
  • Watkins, T
  • Steingrub, J
  • Tidswell, M
  • Braden, E
  • DeSouza, L
  • Germain, J
  • Kardos, C
  • Kelley, D
  • Kozikowski, L
  • Ouellette, S
  • Guntupalli, K
  • Bandi, V
  • Pope, C
  • Ross, C
  • Brower, R
  • Fessler, H
  • Hager, D
  • Mendez-Tellez, P
  • Needham, D
  • Oakjones, K
  • Sevransky, J
  • Workneh, A
  • Shanholtz, C
  • Herr, D
  • Howes, H
  • Netzer, G
  • Rock, P
  • Sampaio, A
  • Titus, J
  • Sloane, P
  • Beck, T
  • Highfield, H
  • King, S
  • Lee, B
  • Bolouri, N
  • Wiedemann, HP
  • Ashton, RW
  • Culver, DA
  • Frederick, T
  • Guzman, JA
  • Komara, JJ
  • Reddy, AJ
  • Hejal, R
  • Andrews, M
  • Haney, D
  • Connors, AF
  • Lasalvia, S
  • Thornton, JD
  • Warren, EL
  • Moss, M
  • Burnham, EL
  • Gray, L
  • Maloney, J
  • Mealer, M
  • Douglas, I
  • Overdier, K
  • Thompson, K
  • Wolken, R
  • Frankel, S
  • McKeehan, J
  • Warner, ML
  • Bost, T
  • Higgins, C
  • Hodgin, K
  • MacIntyre, N
  • Brown, L
  • Cox, C
  • Gentile, M
  • Govert, J
  • Knudsen, N
  • Carson, S
  • Chang, L
  • Choudhury, S
  • et al.
Abstract

© 2015 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins. Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.

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