Fluorescence photon-density waves in optically diffusive media
Abstract
Intensity-modulated light launches traveling photon-density waves into optically diffusive media. In the presence of a fluorophore, excitation photon density waves generate fluorescence photon-density waves that can be quantitatively described using diffusion theory. We examine a number of limiting cases of the fluorescence photon-density wave to clarify its physical meaning and its implications in quantitative fluorescence spectroscopy of diffusive media. Our discussion may guide the development of experimental protocols for quantitative fluorescence spectroscopy in optically diffusive media.
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