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Synthesis of Naturally Racemic Marilines B & C through Multicomponent Reactions Involving ortho -Quinone Methides and Various Nitrogen Nucleophiles
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https://doi.org/10.1055/s-0041-1738443Abstract
Abstract: Herein, we report the first total synthesis of (±)-marilines B and C, as well as a failed approach to (±)-mariline A, by using our recently developed multicomponent reaction method, which involves the interception of ortho-quinone methides with various nitrogen nucleophiles to allow easy assembly of various benzylic amine cores with diverse substituents.
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