Skip to main content
Download PDF
- Main
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
- Pharoah, Paul DP;
- Tsai, Ya-Yu;
- Ramus, Susan J;
- Phelan, Catherine M;
- Goode, Ellen L;
- Lawrenson, Kate;
- Buckley, Melissa;
- Fridley, Brooke L;
- Tyrer, Jonathan P;
- Shen, Howard;
- Weber, Rachel;
- Karevan, Rod;
- Larson, Melissa C;
- Song, Honglin;
- Tessier, Daniel C;
- Bacot, François;
- Vincent, Daniel;
- Cunningham, Julie M;
- Dennis, Joe;
- Dicks, Ed;
- Aben, Katja K;
- Anton-Culver, Hoda;
- Antonenkova, Natalia;
- Armasu, Sebastian M;
- Baglietto, Laura;
- Bandera, Elisa V;
- Beckmann, Matthias W;
- Birrer, Michael J;
- Bloom, Greg;
- Bogdanova, Natalia;
- Brenton, James D;
- Brinton, Louise A;
- Brooks-Wilson, Angela;
- Brown, Robert;
- Butzow, Ralf;
- Campbell, Ian;
- Carney, Michael E;
- Carvalho, Renato S;
- Chang-Claude, Jenny;
- Chen, Y Anne;
- Chen, Zhihua;
- Chow, Wong-Ho;
- Cicek, Mine S;
- Coetzee, Gerhard;
- Cook, Linda S;
- Cramer, Daniel W;
- Cybulski, Cezary;
- Dansonka-Mieszkowska, Agnieszka;
- Despierre, Evelyn;
- Doherty, Jennifer A;
- Dörk, Thilo;
- du Bois, Andreas;
- Dürst, Matthias;
- Eccles, Diana;
- Edwards, Robert;
- Ekici, Arif B;
- Fasching, Peter A;
- Fenstermacher, David;
- Flanagan, James;
- Gao, Yu-Tang;
- Garcia-Closas, Montserrat;
- Gentry-Maharaj, Aleksandra;
- Giles, Graham;
- Gjyshi, Anxhela;
- Gore, Martin;
- Gronwald, Jacek;
- Guo, Qi;
- Halle, Mari K;
- Harter, Philipp;
- Hein, Alexander;
- Heitz, Florian;
- Hillemanns, Peter;
- Hoatlin, Maureen;
- Høgdall, Estrid;
- Høgdall, Claus K;
- Hosono, Satoyo;
- Jakubowska, Anna;
- Jensen, Allan;
- Kalli, Kimberly R;
- Karlan, Beth Y;
- Kelemen, Linda E;
- Kiemeney, Lambertus A;
- Kjaer, Susanne Krüger;
- Konecny, Gottfried E;
- Krakstad, Camilla;
- Kupryjanczyk, Jolanta;
- Lambrechts, Diether;
- Lambrechts, Sandrina;
- Le, Nhu D;
- Lee, Nathan;
- Lee, Janet;
- Leminen, Arto;
- Lim, Boon Kiong;
- Lissowska, Jolanta;
- Lubiński, Jan;
- Lundvall, Lene;
- Lurie, Galina;
- Massuger, Leon FAG;
- Matsuo, Keitaro;
- McGuire, Valerie;
- McLaughlin, John R;
- Menon, Usha;
- Modugno, Francesmary;
- Moysich, Kirsten B;
- Nakanishi, Toru;
- Narod, Steven A;
- Ness, Roberta B;
- Nevanlinna, Heli;
- Nickels, Stefan;
- Noushmehr, Houtan;
- Odunsi, Kunle;
- Olson, Sara;
- Orlow, Irene;
- Paul, James;
- Pejovic, Tanja;
- Pelttari, Liisa M;
- Permuth-Wey, Jenny;
- Pike, Malcolm C;
- Poole, Elizabeth M;
- Qu, Xiaotao;
- Risch, Harvey A;
- Rodriguez-Rodriguez, Lorna;
- Rossing, Mary Anne;
- Rudolph, Anja;
- Runnebaum, Ingo;
- Rzepecka, Iwona K;
- Salvesen, Helga B;
- Schwaab, Ira;
- Severi, Gianluca;
- Shen, Hui;
- Shridhar, Vijayalakshmi;
- Shu, Xiao-Ou;
- Sieh, Weiva;
- Southey, Melissa C;
- Spellman, Paul;
- Tajima, Kazuo;
- Teo, Soo-Hwang;
- Terry, Kathryn L;
- Thompson, Pamela J;
- Timorek, Agnieszka;
- Tworoger, Shelley S;
- van Altena, Anne M;
- van den Berg, David;
- Vergote, Ignace;
- Vierkant, Robert A;
- Vitonis, Allison F;
- Wang-Gohrke, Shan;
- Wentzensen, Nicolas;
- Whittemore, Alice S;
- Wik, Elisabeth;
- Winterhoff, Boris;
- Woo, Yin Ling;
- Wu, Anna H;
- Yang, Hannah P;
- Zheng, Wei;
- Ziogas, Argyrios;
- Zulkifli, Famida;
- Goodman, Marc T;
- Hall, Per;
- Easton, Douglas F;
- Pearce, Celeste L;
- Berchuck, Andrew;
- Chenevix-Trench, Georgia;
- Iversen, Edwin;
- Monteiro, Alvaro NA;
- Gayther, Simon A;
- Schildkraut, Joellen M;
- Sellers, Thomas A
Published Web Location
https://doi.org/10.1038/ng.2564Abstract
Paul Pharoah, Joellen Schildkraut, Thomas Sellers and colleagues report a meta-analysis of genome-wide association studies for epithelial ovarian cancer and genotyping using the iCOGS array in 18,174 cases and 26,134 controls from 43 studies from the Ovarian Cancer Association Consortium. They identify three new ovarian cancer susceptibility loci, including one specific to the serous subtype, and their integrated molecular analysis of genes and regulatory regions at these loci suggests disease mechanisms.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.