Skip to main content
Download PDF
- Main
Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability
- Huynh, Alexandria;
- DuPage, Michel;
- Priyadharshini, Bhavana;
- Sage, Peter T;
- Quiros, Jason;
- Borges, Christopher M;
- Townamchai, Natavudh;
- Gerriets, Valerie A;
- Rathmell, Jeffrey C;
- Sharpe, Arlene H;
- Bluestone, Jeffrey A;
- Turka, Laurence A
Published Web Location
https://doi.org/10.1038/ni.3077Abstract
Regulatory T cells normally maintain high expression of the phosphatase PTEN. Turka and colleagues use conditional deletion of PTEN in regulatory T cells to show that it is critical for their function and stability.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.